#1 DESTINATION FOR WEIGHT LOSS

Unlock Your True Potential with the Buffie Protocol!

A Personalized Path To Lasting Health And Confidence

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Licensed in :

AL, CA, FL, GA, IN, LA, MD, MI
MO, MN, MS, NC, OH, TN, TX, and VA.

Our patients have lost thousands of pounds!

NEW Program

MrsMD Aesthetic Treatments

At MrsMD, we offer advanced aesthetic treatments designed to address a variety of skin concerns, helping you achieve a refreshed, radiant look.

  • Face & Skin Rejuvenation – Restore a youthful glow with Morpheus8 Burst (microneedling + radiofrequency), Lumecca Peak (photo-rejuvenation for sun damage), and Forma/Forma Plus(non-surgical skin tightening).

  • Hair Removal – Achieve smooth, long-lasting results with Diolaze XL Max (for all skin tones) and Fusion Light/Dark (customized for lighter or darker skin).

  • Vascular Treatments – Reduce visible veins and discoloration with Vasculaze Max, targeting spider veins, broken capillaries, and more.

Ready to enhance your natural beauty? Contact us to book a consultation and find the perfect treatment for you!

Introducing MrsMD Lift™

A clinician-guided medical weight management program that combines semaglutide or tirzepatide with NAD+ for eligible patients.

Developed by MrsMD Wellness, MrsMD Lift™ pairs a compounded formulation of semaglutide + NAD+ or tirzepatide + NAD+ with ongoing medical oversight. The program is designed for patients seeking a more personalized metabolic weight management approach, with formulation and dosing determined by a MrsMD provider.

MrsMD Lift™ was designed to support:

  • clinician-guided medical weight management
  • metabolic function
  • cellular energy pathways
  • a personalized treatment plan

 

Medications starting at $195 per month, Shipping included
Provider consultation: $119 per month

Only available in California, Connecticut , District of Columbia, Florida, Georgia, Indiana, Louisiana, Mississippi, Missouri, North Carolina, Ohio, Pennsylvania, Tennessee, Texas, Utah, Washington, and Wisconsin

Availability is limited to eligible patients in states where both MrsMD providers and the dispensing pharmacy are licensed. Prescribing is subject to clinician review and is not guaranteed.

Clinician-Guided Care

Every patient meets monthly with a MrsMD medical provider to review progress, adjust prescriptions as needed, and receive guidance throughout their weight management journey.

Why Patients Choose MrsMD Lift™

Many traditional weight-management treatments can leave patients feeling fatigued or mentally foggy.

MrsMD Lift™ was designed to support:

• Metabolic efficiency
• Cellular energy production
• Muscle preservation
• Sustainable weight management

Our medical providers determine the best formulation for each patient based on their individual metabolic needs.

Start Your MrsMD Lift™ Journey

• Medications starting at $195 per month
• Shipping included
• Clinician-guided care
• Personalized metabolic weight management

NAD+
Therapy

Cost by Dose

Injection (4 week supply)

1x week (30mg): $119.00
2x week (30mg): $199.00
1x week (50mg): $179.00
2x week (50mg): $299.00
IV Infusion – (500mg): $750.00

Nasal Spray (2 month supply)

18mg/Spray: $249.00
36mg/Spray: $449.00

 

 

Zepbound®

Zepbound

Starting at $299 per month

Commercially insured patients*:

  • If you have coverage for the medication you can pay as little as $25 for a 1-month supply of Zepbound with a savings card
  • If it is not covered by your insurance, the price with the savings card is $499 for a 1-month supply of auto injectors at all doses (2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg)

Uninsured and self-pay price is: 

$299 – $449 for a 1-month supply of Zepbound vials or KwikPen injector

*Government beneficiaries are excluded †FSA/HSA cards are accepted

Wegovy®

 

Starting at $199 per month

Commercially insured patients:

Patients who have coverage for the medication can pay as little as $0 for a 1-month supply of Wegovy with a savings card*

Uninsured and self-pay price is

$199 – $349 for a 1-month supply of Wegovy

*Government beneficiaries are excluded

†FSA/HSA cards are accepted

Requires MrsMD Membership

Lost Over
0 +

pounds

WHO WE ARE

It's Time To Reclaim Control Of Your Life, And Unlock The Vibrant, Confident You That You've Always Wanted To Be.

If you're tired of the endless cycle of weight loss frustrations, it's time for a change. The Buffie Protocol is different – it's not just about losing weight; it's about regaining control of your health. 

Our program combines medically-backed solutions, personalized medications, transformative therapy, and a holistic approach to nutrition and fitness. We understand that weight management is about more than just numbers on a scale; it's about addressing both the physical and emotional aspects of your journey. Say goodbye to quick fixes and hello to lasting results.

FINANCE – Now Accepting

With a personalized plan

that includes medically-backed solutions, tailored medications, transformative therapy, and a holistic approach to nutrition and fitness, you'll have the tools you need to succeed.

How it works

Start With A Personalized Plan That Includes :

Expert Help

Get guidance from top providers in the field.

Trusted Meds

Safe, doctor-approved solutions tailored to your needs.

All About You

Personalized treatments designed with your goals in mind.

Continuous Care

Support at every step of your wellness journey.

Witness The Power Of The Buffie Protocol

What Clients, are Saying

Are you wondering what real results look like with The Buffie Protocol? Let the visual evidence speak for itself. We're proud to showcase the remarkable transformations of individuals who have embraced this life-changing program. These before and after photos are not just about weight loss; they're about reclaiming health, boosting confidence, and redefining what's possible.

Terry - lost 133lbs

Desirae - lost 165lbs

Courtney - lost 150lbs

Brandon - lost 75lbs

Alex - lost 55lbs

Gee Gee - lost 40lbs

Shannon - lost 165lbs

Terry - lost 133lbs

***Some of our customers purchased their products, while others received them for free in exchange for feedback. Customer results have not been independently verified, and individual outcomes may vary. MrsMD customers have reported an average weight loss of 11 lbs within 4 weeks after their initial consultation while participating in our weight loss program, which includes Semaglutide or Tirzepatide.  The MrsMD weight loss program is a holistic solution that combines personalized nutrition guidance, advanced tools, and anti-obesity medication, as determined by your healthcare provider, along with a reduced-calorie diet and regular exercise. Brand medications such as Wegovy and Zepbound are FDA-approved for the treatment of obesity. Stopping treatment can lead to weight regain.

MrsMD® Tailored Weight Loss Journey

Embark on a personalized and empowering weight loss journey with MrsMD®. Our program is structured into four steps, each designed to support and guide you toward your health goals with our unique MrsMD touch.

  • Step 1:

    Personalized Planning

  • Step 2

    Monitoring and Adjustment

  • Step 3

    Support and Guidance

  • Step 4

    Evaluation and Maintenance

Personalized Planning

Progress Pathway: Monitoring and Adjustment

Continual Care: Support and Guidance

Milestone Marker: Evaluation and Maintenance

Conclusion: Begin your transformation with MrsMD®. Schedule your first consultation and take a step towards a healthier, more fulfilled you.

Prescribing Wegovy and Zepbound For Effective Obesity Treatment

At MrsMD Weight Loss, we offer safe, brand-name treatments for patients without insurance. Our goal is to provide accessible anti-obesity treatment while adhering to strict safety and quality standards.

Our Program

The Buffie Protocol

More Than a Program — A Guided Transformation

The Buffie Protocol is a personalized journey toward better health, sustainable weight management, and renewed confidence. Inspired by Buffie Purselle’s own transformation, this approach combines medical guidance, metabolic support, and lifestyle strategies designed to help you achieve lasting results.

These before-and-after images reflect the power of individualized care, physician-guided treatment, and a comprehensive approach to nutrition, movement, and metabolic health.

At MrsMD Wellness, our medical providers work with you every step of the way — helping you adjust treatment, stay motivated, and maintain progress as your body changes.

Your transformation can start today.

Provider-Guided Care

Patients enrolled in our programs meet with a MrsMD medical provider each month to:

  • Review progress and health goals
  • Adjust prescriptions and dosing as needed
  • Receive guidance and support throughout their weight-management journey
  • Ensure treatment remains safe and effective


Monthly Provider Consultation: $119

This monthly visit allows our providers to continue prescribing appropriate treatments and support you throughout your journey.

Start Your Journey

Your transformation starts with the first step.

Have A Question?

Frequently Asked Questions

Explore our comprehensive FAQ section to find answers to all your questions. Whether you're curious about our services, billing, or anything in between, we've got you covered. Our detailed answers provide the clarity you need to make informed decisions about your health and wellness journey.

Feeling Drained by Perimenopause or Menopause? NAD+ Can Help!

Perimenopause and menopause can bring a host of challenging symptoms, from fatigue and brain fog to mood swings and weight management difficulties.

NAD+ therapy may offer a natural way to revitalize your health and well-being.

MrsMD® Watch This Video

The MrsMD Buffie Purselle and Dr David Purselle show you how to properly inject yourself.

Team

Meet Our Team

Get to know the dedicated professionals behind Noura. Our team is comprised of passionate individuals with diverse expertise, united by a common goal: to empower you on your journey to optimal health and wellness.

Buffie Purselle

Buffie Purselle

Founder & CEO

David Purselle

David Purselle

Medical Director

Linda Yatak, MSN

Linda Yatak, MSN

Psychiatric Nurse Practitioner

Tola Omolayo, PA-C

Tola Omolayo, PA-C

Physician Assistant

Heather Hughes

Heather Hughes

HR Director

Dayana Garcia

Dayana Garcia

Patient Care Specialist

Brenda Garcia

Brenda Garcia

Patient Care Specialist

Chris Weldon

Chris Weldon

Lead TMS Technician

facebook Group

Join the MrsMD® Weight Loss Support Group

Join Our Journey to Transformation: Become a part of the MrsMD® Weight Loss community, where we conquer challenges, celebrate milestones, and support each other every step of the way. Click 'Join Group' to start your path to a healthier, happier you with friends who care!